Staff Profile

School of Science and Technology People   Key Staff   Staff Profile  
Dr. Lau Po Ying Carol 劉寶盈博士
BSc (Hons) HKU, PhD HKU
Lecturer
School of Science and Technology

Biography

Dr. Carol Lau obtained her Bachelor of Science and Doctor of Philosophy in the University of Hong Kong. She worked in the Department of Orthopedics and Traumatology, and School of Biomedical Sciences, respectively in the Chinese University of Hong Kong before joining Hong Kong Metropolitan University. Dr. Lau has research interests on Plant Reproductive Biology, Tumorigenesis and Pathology of Bone Tumors, and Raman Spectroscopy.

 

Teaching Areas & Research Interests

  • Plant Reproductive Biology
  • Tumorigenesis and Pathology of Bone Tumors
  • Raman Spectroscopy

Selected Publications

Journal Articles

  • Carol PY Lau*, Wenao Ma, Kwan Yau Law, Maribel Lacambra, Kwok Chuen Wong, Chien Wei Lee, Oscar Lee, Qi Dou, Shekhar Madhukar Kumta. Development of Deep Learning Algorithms to Discriminate Giant Cell Tumor of Bone from Adjacent Normal Tissues by Confocal Raman Spectroscopy. Analyst, 2022,147, 1425-1439
  • Carol P. Y. Lau*, Cathy S. H. Fung, Kwok Chuen Wong, Yu-Hsuan Wang, Lin Huang, Stephen K. W. Tsui, Oscar K. Lee, Shekhar M. Kumta. Simvastatin Possesses Antitumor and Differentiation‐Promoting Properties That Affect Stromal Cells in Giant Cell Tumor of Bone. Journal of Orthopaedic Research 2020-02-11 | journal-article DOI: 10.1002/jor.24456
  • Xi Zeng, Joseph Chi-Ching Tsui, Mai Shi, Jie Peng, Cyanne Ye Cao, Lea Ling-Yu Kan, Carol Po-Ying Lau, Yonghao Liang , Lingyi Wang , Li Liu, Zhiwei Chen, Stephen Kwok-Wing Tsui. Genome-Wide Characterization of Host Transcriptional and Epigenetic Alterations During HIV Infection of T Lymphocytes. Front Immunol. 2020 Sep 10;11:2131. DOI: 10.3389/fimmu.2020.02131. eCollection 2020.
  • Xiao-Yu Liu, Kevin Yi Yang, Ming-Qiang Wang, Jamie Sui-Lam Kwok, Xi Zeng, Zhiyuan Yang, Xiao-Jun Xiao, Carol Po-Ying Lau, Ying Li, Zhi-Ming Huang, Jin-Ge Ba, Aldrin Kay-Yuen Yim, Chun-Yan Ouyang, Sai-Ming Ngai, Ting-Fung Chan, Elaine Lai-Han Leung, Liang Liu, Zhi-Gang Liu, Stephen Kwok-Wing Tsui. High-quality assembly of Dermatophagoides pteronyssinus genome and transcriptome reveals a wide range of novel allergens. Journal of Allergy and Clinical Immunology 2018 | journal-article DOI: 10.1016/j.jaci.2017.11.038
  • Patrick Kwok Shing Ng, Carol Po Ying Lau*, Emily Kai Yee Lam, Sheila Sai Kam Li, Vivian Wai Yan Lui, Winnie Yeo, Yuen Keng Ng, Paul Bo San Lai & Stephen Kwok Wing Tsui. Hypermethylation of NF-kappa B-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis. Digestive Diseases and Sciences 2018 | journal-article DOI: 10.1007/s10620-018-4929-3
  • Carol P.Y. Lau*, Jamie S.L. Kwok, Joseph C.C. Tsui, Lin Huang, Kevin Y. Yang, Stephen K.W. Tsui, Shekhar Madhukar Kumta. Genome-Wide Transcriptome Profiling of the Neoplastic Giant Cell Tumor of Bone Stromal Cells by RNA Sequencing. Journal of Cellular Biochemistry 2017 | journal-article DOI: 10.1002/jcb.25792
  • Shihui Chen, Carol Po ying Lau, Ming Lei, Jiang Peng, Tao Tang, Xiaohong Wang, Ling Qin, Shekhar-Madhukar Kumta. Segmental composite porous scaffolds with either osteogenesis or anti-bone resorption properties tested in a rabbit ulna defect model. Journal of Tissue Engineering and Regenerative Medicine 2017 | journal-article DOI: 10.1002/term.1828
  • Shekhar Kumta, Carol PY Lau, KC Wong. Systemic Adjuvant Therapies in the Management of Giant Cell Tumor of Bone: Current State of Understanding and Practice. Journal of Bone and Soft Tissue Tumors Sep-Dec 2017;3(2): 6-9
  • Joseph Chi-Ching Tsui, Carol Po-Ying Lau*, Alex Chun Cheung, Kwok-Chuen Wong, Lin Huang, Stephen Kwok-Wing Tsui, Shekhar Madhukar Kumta. Differential expression of filamin B splice variants in giant cell tumor cells. Oncology Reports 2016 | journal-article DOI: 10.3892/or.2016.5197
  • Carol P. Y. Lau*, Kwok Chuen Wong, Lin Huang, Gang Li, Stephen K.W. Tsui, Shekhar Madhukar Kumta. A mouse model of luciferase-transfected stromal cells of giant cell tumor of bone. Connective Tissue Research 2015 | journal-article DOI: 10.3109/03008207.2015.1075519
  • Carol P. Y. Lau*, Lin Huang, Kwok Chuen Wong, Shekhar Madhukar Kumta. Comparison of the anti-tumor effects of denosumab and zoledronic acid on the neoplastic stromal cells of giant cell tumor of bone. Connective Tissue Research 2013 | journal-article DOI: 10.3109/03008207.2013.848202
  • Wayne Y.W. Lee, Ting Zhang, Carol P.Y. Lau, C.C. Wang, Kai-Ming Chan, Gang Li. Immortalized human fetal bone marrow-derived mesenchymal stromal cell expressing suicide gene for anti-tumor therapy in vitro and in vivo. Cytotherapy 2013 | journal-article DOI: 10.1016/j.jcyt.2013.06.010
  • Carol Po Ying Lau*, Patrick Kwok Shing Ng, Man Shan Li, Stephen Kwok Wing Tsui, Lin Huang, Shekhar Madhukar Kumta. p63 regulates cell proliferation and cell cycle progression-associated genes in stromal cells of giant cell tumor of the bone. International Journal of Oncology 2013 | journal-article DOI: 10.3892/ijo.2012.1727
  • T Tang, G Zhang, Carol PY Lau, L Z Zheng, X H Xie, X L Wang, X H Wang, K He, Y Patrick, L Qin. Effect of water-soluble P-chitosan and S-chitosan on human primary osteoblasts and giant cell tumor of bone stromal cells. Biomedical Materials 2011 | journal-article DOI: 10.1088/1748-6041/6/1/015004
  • Carol P.Y. Lau*, Lin Huang, Stephen K.W. Tsui, Patrick K.S. Ng, Pui-Yin. Leung, Shekhar M. Kumta. Pamidronate, Farnesyl Transferase, and Geranylgeranyl Transferase-I Inhibitors Affects Cell Proliferation, Apoptosis, and OPG/RANKL mRNA Expression in Stromal Cells of Giant Cell Tumor of Bone. Journal of Orthopaedic Research 2011 | journal-article DOI: 10.1002/jor.21249
  • Patrick Kwok-Shing Ng, Stephen Kwok-Wing Tsui, Carol Po-Ying Lau, Chi-Hang Wong, Winnie Hiu-Ting Wong, Lin Huang, Shekhar-Madhukar Kumta. CCAAT/Enhancer Binding Protein Beta Is Up-Regulated in Giant Cell Tumor of Bone and Regulates RANKL Expression. Journal of Cellular Biochemistry 2010 | journal-article DOI: 10.1002/jcb.22556
  • Carol P. Y. Lau*, Richard M. K. Saunders, Lawrence Ramsden. Floral biology, breeding systems and population genetic structure of three climbing Bauhinia species (Leguminosae: Caesalpinioideae) in Hong Kong, China. Journal of Tropical Ecology 2009 | journal-article DOI: 10.1017/S0266467408005762
  • Carol P. Y. Lau*, Lawrence Ramsden, Richard M. K. Saunders. Hybrid origin of "Bauhinia blakeana" (Leguminosae : Caesalpinioideae), inferred using morphological reproductive, and molecular data. American Journal of Botany 2005 | journal-article DOI: 10.3732/ajb.92.3.525

Modified Date: 07 Jul, 2022
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Jonathan Chiu
Marketing Director
3DP Technology Limited

Jonathan handles all external affairs include business development, patents write up and public relations. He is frequently interviewed by media and is considered a pioneer in 3D printing products.

Krutz Cheuk
Biomedical Engineer
Hong Kong Sanatorium & Hospital

After graduating from OUHK, Krutz obtained an M.Sc. in Engineering Management from CityU. He is now completing his second master degree, M.Sc. in Biomedical Engineering, at CUHK. Krutz has a wide range of working experience. He has been with Siemens, VTech, and PCCW.

Hugo Leung
Software and Hardware Engineer
Innovation Team Company Limited

Hugo Leung Wai-yin, who graduated from his four-year programme in 2015, won the Best Paper Award for his ‘intelligent pill-dispenser’ design at the Institute of Electrical and Electronics Engineering’s International Conference on Consumer Electronics – China 2015.

The pill-dispenser alerts patients via sound and LED flashes to pre-set dosage and time intervals. Unlike units currently on the market, Hugo’s design connects to any mobile phone globally. In explaining how it works, he said: ‘There are three layers in the portable pillbox. The lowest level is a controller with various devices which can be connected to mobile phones in remote locations. Patients are alerted by a sound alarm and flashes. Should they fail to follow their prescribed regime, data can be sent via SMS to relatives and friends for follow up.’ The pill-dispenser has four medicine slots, plus a back-up with a LED alert, topped by a 500ml water bottle. It took Hugo three months of research and coding to complete his design, but he feels it was worth all his time and effort.

Hugo’s public examination results were disappointing and he was at a loss about his future before enrolling at the OUHK, which he now realizes was a major turning point in his life. He is grateful for the OUHK’s learning environment, its industry links and the positive guidance and encouragement from his teachers. The University is now exploring the commercial potential of his design with a pharmaceutical company. He hopes that this will benefit the elderly and chronically ill, as well as the society at large.

Soon after completing his studies, Hugo joined an automation technology company as an assistant engineer. He is responsible for the design and development of automation devices. The target is to minimize human labor and increase the quality of products. He is developing products which are used in various sections, including healthcare, manufacturing and consumer electronics.

Course CodeTitleCredits
 COMP S321FAdvanced Database and Data Warehousing5
 COMP S333FAdvanced Programming and AI Algorithms5
 COMP S351FSoftware Project Management5
 COMP S362FConcurrent and Network Programming5
 COMP S363FDistributed Systems and Parallel Computing5
 COMP S382FData Mining and Analytics5
 COMP S390FCreative Programming for Games5
 COMP S492FMachine Learning5
 ELEC S305FComputer Networking5
 ELEC S348FIOT Security5
 ELEC S371FDigital Forensics5
 ELEC S431FBlockchain Technologies5
 ELEC S425FComputer and Network Security5
 Course CodeTitleCredits
 ELEC S201FBasic Electronics5
 IT S290FHuman Computer Interaction & User Experience Design5
 STAT S251FStatistical Data Analysis5
 Course CodeTitleCredits
 COMPS333FAdvanced Programming and AI Algorithms5
 COMPS362FConcurrent and Network Programming5
 COMPS363FDistributed Systems and Parallel Computing5
 COMPS380FWeb Applications: Design and Development5
 COMPS381FServer-side Technologies and Cloud Computing5
 COMPS382FData Mining and Analytics5
 COMPS390FCreative Programming for Games5
 COMPS413FApplication Design and Development for Mobile Devices5
 COMPS492FMachine Learning5
 ELECS305FComputer Networking5
 ELECS363FAdvanced Computer Design5
 ELECS425FComputer and Network Security5