Human Biochemistry

SCI 8030SEF

Course Guide

Human Biochemistry

SCI 8030SEF

Course Guide

Human Biochemistry

Course Start Date

N/A

Course Level

N/A

Length in Terms

N/A

Credits

N/A

Language

N/A

Fees ($) (including lab fees)

N/A

Future Terms

Quota and Schedule

Course Start Date	Course Level	Length in Terms	Credits	Language	Fees ($) (including lab fees)	Future Terms
N/A	N/A	N/A	N/A	N/A	N/A

Quota and Schedule

Course Coordinator:

Dr Kelvin Chan Yuen Kwong

BSc in Biochemistry and Chemistry
PhD in Pathology
Registered MLT (Part I) HK

Course Developer:

TBC

COMP 2010SED Computing Fundamentals with Java is a two-term, six-credit-unit, 2000-level course within the Bachelor of Computing with Honours in Internet Technology (BCITH) programme suite and the Bachelor of Science with Honours in Computing and Networking (BSCICNH) programme suite. It is a compulsory course for BCITH and BSCICNH. This course is designed to provide a solid foundation in the fundamentals of computing and is suitable for students who do not have prior experience in programming. The problem solving aspect of computing will be emphasised. The main focus is to learn an object-oriented programming language (Java) and use it to solve problems. The software development cycle will also be introduced.

Advisory Prerequisite(s)

PUAD 2002AED

Aims

The aim of this course is to provide students with an understanding of the chemistry of crucial important biological molecules, including proteins, carbohydrates, lipids and nucleic acids. The focus is on their metabolic functions within biological systems, as well as at the molecular and cellular levels. This foundational knowledge will serve as a basis for further studies in biomedical-related disciplines.

Contents

Topic 1. Water and aqueous system

Properties of water
Interactions and bonding
Ionisation of water, weak acids and weak bases
Mechanism of blood pH and buffer system

Topic 2. Chemistry of carbohydrates, protein, lipids and nucleic acids

Definition and classification of carbohydrates, protein, lipids and nucleic acids
Structure, chemical properties and functions of carbohydrates, protein, lipids and nucleic acids

Topic 3. Biological oxidations

Introduction, enzymes & coenzymes of biological oxidation
Electron transport chain or respiratory chain
Oxidative phosphorylation, inhibitors & uncouplers of oxidative phosphorylation
Pyruvate oxidation & citric acid cycle

Topic 4. Energy metabolism

Glycolysis and aerobic respiration
Pentose phosphate pathway of NADPH
Glucogenic & ketogenic amino acids
Metabolism of ketone bodies
Fatty acid and lipids metabolism
Related disorders such as glycosuria and diabetes mellitus

Topic 5. Hemoglobins

Chemistry & functions of haemoglobin
Introduction to heme synthesis
Heme degradation and types of normal and abnormal hemoglobin
Types of jaundice

Topic 6. Enzymes

Types, properties, classification and nomenclature
Definition of zymogen and proenzyme
Co-factors and comparison of free energy of activation
Classification of enzymes
Specificity factors affecting enzymes activity
Enzyme inhibition
Isoenzymes
Diagnostic importance of different enzymes

Learning support

Lecture: 22 hours

Tutorial: 11 hours

Laboratory: 6 hours

Assessment

Course assessment includes continuous assessment and a final written examination. Continuous assessment includes laboratory reports, presentations, and a mid-term test.

Online requirement

Students are required to submit assignments via the Online Learning Environment (OLE).

Equipment

A PC-compatible computer ready for connecting to the Internet is essential. The minimum configuration of the computer is:

PC with an x86 CPU or equivalent
1GB RAM
Hard disk
Sound card with speakers

You need to be familiar with the basic use of a computer including keyboard, mouse and word processing software. Experience in using email, the Internet and the World Wide Web is also essential.

Software

You should have Windows with Microsoft Word. Other software will be downloaded from the Internet. You may need to use OpenOffice to prepare assignment answers.

Set book(s)

There is no set book in this course.

Students with disabilities or special educational needs

The audio and visual components of this course may cause difficulties for students with an audio or visual handicap. You are encouraged to seek advice from the Course Coordinator before enrolling on this course.