Staff Profile

Biography

Dr PL Chan received his Bachelor of Science (Hons) degree in Biochemistry and Master of Philosophy degree in Microbiology from the Chinese University of Hong Kong. He then pursued his interests in influenza and immune cell biology research and obtained his doctorate in immunology from the University of Hong Kong. Dr Chan continued his research work at the University of Hong Kong before joining the School of Science and Technology of the then Open University of Hong Kong in 2015 as a teaching assistant. He then moved to the position of lecturer and assistant professor. He assumed the position of assistant professor of the School of Nursing and Health Studies in 2022.

His current research interest is in the effect of antibiotics and pollutants on microbiome and resistome in food, manure, farm soil, and microplastics. He is also interested in the immunology of inflammatory bowel diseases and the immunotoxicities of pollutant of emerging concerns

Apart from research, Dr Chan also enjoys teaching and concerns about the moral and value education of students. He has earned the Master of Art in Ethics and Public Affairs with Distinction in the Hong Kong Baptist University. 

Teaching Areas & Research Interests

• Microbiome and resistome in food, manure, and farm soil
• Microbiome and resistome in microplastics
• Immunotoxicity of pollutant of emerging concerns
• Immunology of inflammatory bowel disease

Academic & Professional Experience

• Member of Royal Society of Biology
• Senate Member (2018 - 2020)

 

Selected Publications

Journal Articles

• Lee TCH, Chan PL, Tam NFY, Xu SJL, Lee FWF (2021). Establish Axenic Cultures of Armored and Unarmored Marine Dinoflagellate Species Using Density Separation, Antibacterial Treatments and Stepwise Dilution Selection. Scientific Reports Sci Rep 11, 202. https://doi.org/10.1038/s41598-020-80638-x
• Lam KL, Kong WP, Ling PY, Lau, TH, Ho KH, Lee FF, Chan, PL. (2020) Antibiotic-Resistant Bacteria in Hydroponic Lettuce in Retail: A Comparative Survey. Foods 9:1327.
• Fung KL, Chan PL. (2020). Comment on: COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression. Journal of Antimicrobial Chemotherapy, dkaa169, https://doi.org/10.1093/jac/dkaa169
• Lee TCH, Chan PL, Xu SJL, Lee FWF (2020) Comparison of growth and toxicity responses between non-toxic and toxic strains of Prorocentrum hoffmannianum. Aquat Biol 29:59-70. https://doi.org/10.3354/ab00725
• Zheng, J., Chan, P.L., Liu, Y.P., Qin, G., Zheng, X., Lam, K.T., Lewi,s D.B., Lau, Y.L. and Tu, W. (Dec 2013). ICOS regulates the generation of functional human CD4+ Treg in a CTLA-4 dependent manner. PLoS One. 8(12):e82203
• Chan. P.L., Zheng, J., Liu, Y., Liu, Y.P., Lam, K.T., Liu, Y., Zheng, X., Lau, Y.L., and Tu, W. (Jul 2013). TLR5 signaling enhances the proliferation of human allogenic CD40-activated B cell induced CD4hiCD25+ regulatory T cells. PLoS One. 8(7):e67969.
• Tu, W., Mao, H., Zheng, J., Liu, Y., Chiu, S.S., Qin, G., Chan, P.L., Lam, K.T., Guan, J., Zhang, L., Guan, Y., Yuen, K.Y., Peiris, J.S., and Lau, Y.L. (Jul 2010). Cytotoxic T lymphocytes established by seasonal human influenza cross-react against pandemic H1N1 influenza virus. J Virol. 84 (13), 6527–6535.
• Zheng, J., Liu, Y., Qin, G., Chan, P.L., Mao, H., Lam, K.T., Lewis, D.B., Lau, Y.L., and Tu, W. (Sep 2009). Efficient induction and expansion of human alloantigen-specific CD8 regulatory T cells from naïve precursors by CD40-activated B cells. J Immunol. 183 (6), 3742–3750.
• Mao, H., Tu, W., Qin, G., Law, H.K., Sia, S.F., Chan, P.L., Liu, Y., Lam, K.T., Zheng, J., Peiris, J., Peiris, M., and Lau, Y.L. (Sep 2009). Influenza virus directly infects human natural killer cells and induces cell apoptosis. J Virol. 83 (18), 9215–9222.
• Tu W., Lau Y.L., Zheng J., Liu Y., Chan P.L., Mao H., Dionis K., Schneider P., and Lewis D.B. (Sep 2008). Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naïve precursors by CD40-activated B cells. Blood. 112 (6),2554–2562.

Selected Professional & Community Services

• Reviewer of International Journal of Environmental Research and Public Health

Further Information

Link to Google Scholar page

Modified Date: 30 Mar, 2023
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